After reading 4thof6’s post, I was compelled to comment.
I think anyone who says science has all the answers is wrong. The only heresy in science is to make a claim that cannot be tested. There are far more than thirteen questions that have scientists puzzled. The great thing about science is that they give awards for disproving established theories. Vera Rubin is quoted in the New Scientist as saying, “If I could have my pick, I would like to learn that Newton’s laws must be modified in order to correctly describe gravitational interactions at large distances.” Lots of incorrect theories and dearly held beliefs have been disproven and many more will go the way of the four humors and a flat earth. Mysteries will remain, but the important thing is to never stop asking questions.